A low BUN value may be caused by a diet very low in protein, by malnutrition, or by severe liver damage.A very high BUN-to-creatinine ratio may be caused by bleeding in the digestive tract or respiratory tract. High BUN-to-creatinine ratios occur with sudden (acute) kidney problems, which may be caused by shock or severe dehydration.A high BUN value may be caused by a high-protein diet, Addison's disease, or tissue damage (such as from severe burns), or from bleeding in the gastrointestinal tract. ![]() Be sure to tell your doctor about all the non-prescription and prescription medicines you take. High BUN levels can also be caused by low blood flow to the kidneys caused by dehydration or heart failure. Kidney damage can be caused by diabetes or high blood pressure that directly affects the kidneys.
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